Advances in liposomal drug delivery: Formulation and optimization

This abstract discusses advances in the field of liposome research, focusing on their nano-details, functionalization, and commercialization. Liposomes, which are bio-degradable and bio-compatible phospholipid bilayer vesicles, are favored carriers for conveying both hydrophobic and hydrophilic bioactives. Clinically, liposomal medicate conveyance frameworks are utilized to treat cancer, contagious contaminations, and viral contaminations, with many advanced clinical trials. The development of liposomes has evolved to meet clinical and industrial demands, including ligand acquisition, long circulation, and stimuli responsiveness. This chapter will focus on liposomes. We will consider how liposomes are formed and the various strategies for preparation and recognize important examples of their applicability in the real world. Liposomes are of particular interest for their clinical applications in multiple contexts, including imaging, vaccination, and gene delivery. Moreover, we will focus on the physical and chemical factors that influence liposome stability, and will highlight materials that could be used to coat liposomes to enhance stability for use in pharmaceuticals and food products.